Phenotypes associated with this allele

• Allele Symbol: Prl7b1^{tm1(KOMP)Vlcg}
• Allele Name: targeted mutation 1, Velocigene
• Allele ID: MGI:3800059
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prl7b1^tm1(KOMP)Vlcg/Prl7b1^tm1(KOMP)Vlcg	involves: C57BL/6NTac	MGI:6112622

Genotype
MGI:6112622

hm1

• Allelic Composition: Prl7b1^{tm1(KOMP)Vlcg}/Prl7b1^{tm1(KOMP)Vlcg}
• Genetic Background: involves: C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:236336 )

N • mice exhibit normal reproduction and placental structure

embryo

abnormal placenta vasculature ( J:236336 )

• maternal hypoxia exposure fails to induce a reorganization of the placenta as observed in wild-type mice

growth/size/body

increased fetal weight ( J:236336 )

• even when expressed as a fraction of placental weight in female mice exposed to low oxygen conditions

cardiovascular system

abnormal placenta vasculature ( J:236336 )

• maternal hypoxia exposure fails to induce a reorganization of the placenta as observed in wild-type mice

cellular

maternal effect ( J:236336 )

• increased fetal survival in female mice exposed to low oxygen conditions