Phenotypes associated with this allele

• Allele Symbol: Rdh10^m366Asp
• Allele Name: mutation 366, Andrew S Peterson
• Allele ID: MGI:3799307
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rdh10^m366Asp/Rdh10^m366Asp	involves: C57BL/6J	MGI:4437875
cx2	Rdh10^m366Asp/Rdh10^m366Asp Tg(Rr291-lacZ)#Mekk/0	involves: C57BL/6J * FVB/N	MGI:3802479

Genotype
MGI:4437875

hm1

• Allelic Composition: Rdh10^m366Asp/Rdh10^m366Asp
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:157301 )

N • mice exhibit normal meninges

abnormal forebrain morphology ( J:157301 )

• at E13.5, the dorsal forebrain is longer and thinner Tuj1+ layer than in wild-type mice

abnormal cerebral cortex morphology ( J:157301 )

• thinner than normal at E16.5

vision/eye

abnormal eye morphology ( J:157301 )

• mice exhibit similar defects as observed in Rdh10^trex homozygotes

craniofacial

abnormal craniofacial morphology ( J:157301 )

• mice exhibit similar defects as observed in Rdh10^trex homozygotes

limbs/digits/tail

abnormal limb morphology ( J:157301 )

• mice exhibit similar defects as observed in Rdh10^trex homozygotes

Genotype
MGI:3802479

cx2

• Allelic Composition: Rdh10^m366Asp/Rdh10^m366Asp; Tg(Rr291-lacZ)#Mekk/0
• Genetic Background: involves: C57BL/6J * FVB/N

nervous system

thin cerebral cortex ( J:136795 )

• at E14.5, mice exhibit a thinner but expanded cortex compared to wild-type mice