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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kcnn4tm1.1Jele
targeted mutation 1.1, Jens Leipziger
MGI:3795277
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kcnn4tm1.1Jele/Kcnn4tm1.1Jele either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) MGI:3797781


Genotype
MGI:3797781
hm1
Allelic
Composition		 Kcnn4tm1.1Jele/Kcnn4tm1.1Jele
Genetic
Background		 either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnn4tm1.1Jele mutation (0 available); any Kcnn4 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
abnormal digestive system physiology ( J:135743 )
• basolateral carbachol stimulated NaCl secretion after forskolin prestimulation is significantly reduced
• however, K+ secretion is similar to wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory