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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ednrbtm1.1Yko
targeted mutation 1.1, Yuri Kotelevtsev
MGI:3795226
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ednrbtm1.1Yko/Ednrbtm1.1Yko involves: 129P2/OlaHsd * Bkl:BKW * C57BL/6 * SJL MGI:3804906


Genotype
MGI:3804906
hm1
Allelic
Composition		 Ednrbtm1.1Yko/Ednrbtm1.1Yko
Genetic
Background		 involves: 129P2/OlaHsd * Bkl:BKW * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrbtm1.1Yko mutation (0 available); any Ednrb mutation (106 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:135711 )
• die shortly after weaning

pigmentation
white spotting ( J:135711 )
• white coat spotting

cardiovascular system
decreased vasodilation ( J:135711 )
• tracheas show no contractile response to S6c, a selective Ednrb agonist

digestive/alimentary system

muscle
decreased vasodilation ( J:135711 )
• tracheas show no contractile response to S6c, a selective Ednrb agonist

integument
white spotting ( J:135711 )
• white coat spotting




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory