Phenotypes associated with this allele

• Allele Symbol: Tg(ACTA1-Ar)78Kyjo
• Allele Name: transgene insertion 78, Cynthia L Jordan
• Allele ID: MGI:3794205
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(ACTA1-Ar)78Kyjo/0	Not Specified	MGI:3794208

Genotype
MGI:3794208

tg1

• Allelic Composition: Tg(ACTA1-Ar)78Kyjo/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:127205 )

• only half of male mice born survive to weaning

postnatal lethality ( J:127205 )

• only half of male mice born survive to weaning

muscle

abnormal skeletal muscle fiber morphology ( J:127205 )

• male mice exhibit atrophic and hypertrophic fibers, internal myonuclei, fiber splitting, altered myofibrillar organization and an overall increase in oxidative metabolism

growth/size/body

decreased body weight ( J:127205 )

• in male mice

behavior/neurological

behavior/neurological phenotype ( J:127205 )

N • mice exhibit normal motor function unlike in Tg(ACTA1-Ar)141Kyjo mice

nervous system

nervous system phenotype ( J:127205 )

N • mice do not exhibit axonopathy unlike in Tg(ACTA1-Ar)141Kyjo mice