Phenotypes associated with this allele

• Allele Symbol: Foxp2^N549K
• Allele Name: Asp549Lys
• Allele ID: MGI:3793745
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Foxp2^N549K/Foxp2^N549K	involves: BALB/c * C3H/HeH	MGI:3795714

Genotype
MGI:3795714

hm1

• Allelic Composition: Foxp2^N549K/Foxp2^N549K
• Genetic Background: involves: BALB/c * C3H/HeH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:135404 )

• mice die at 3 to 5 months

nervous system

abnormal cerebellar foliation ( J:135404 )

• decreased foliation is not as severe as in Foxp2^R552H or Foxp2^S321X homozygotes

small cerebellum ( J:135404 )

• mice exhibit smaller than normal cerebellum but the reduction in size that is not as severe as in Foxp2^R552H or Foxp2^S321X homozygotes

behavior/neurological

abnormal righting response ( J:135404 )

• mice exhibit a delay in the maturation of the righting reflex that is not as severe as in Foxp2^R552H or Foxp2^S321X homozygotes

growth/size/body

slow postnatal weight gain ( J:135404 )

• mice exhibit slow postnatal weight gain that is not as severe as in Foxp2^R552H or Foxp2^S321X homozygotes