All Phenotypes Csnk1e<tm1Asil> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Csnk1e^tm1Asil
targeted mutation 1, Andrew S I Loudon
MGI:3793318

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Csnk1e^tm1Asil/Csnk1e^tm1Asil	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:3804020
ht2	Csnk1e^tm1Asil/Csnk1e⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:3804017
ht3	Csnk1e^tm1Asil/Csnk1e^tm1.1Asil	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:3804021

Allelic Composition	Csnk1e^tm1Asil/Csnk1e^tm1Asil
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csnk1e^tm1Asil mutation (1 available); any Csnk1e mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

shortened circadian behavior period ( J:135186 )

• mutant mice are viable and fertile with no overt deleterious phenotype

• significant shortening of circadian period of behavior in vivo in a gene dose-dependent manner

• homozygous mice have 3.6 hr shorter circadian period than wild-type

nervous system

abnormal neuron physiology ( J:135186 )

• significant shortening of circadian period of suprachiasmatic nucleus firing rates in vitro in a gene dose-dependent manner

Allelic Composition	Csnk1e^tm1Asil/Csnk1e⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csnk1e^tm1Asil mutation (1 available); any Csnk1e mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

shortened circadian behavior period ( J:135186 )

• significant shortening of circadian period of behavior in vivo in a gene dose-dependent manner

• heterozygous mice have 1.8 hr shorter circadian period than wild-type

• mutant mice are viable and fertile with no overt deleterious phenotype

nervous system

abnormal neuron physiology ( J:135186 )

• significant shortening of circadian period of suprachiasmatic nucleus firing rates in vitro in a gene dose-dependent manner

Allelic Composition	Csnk1e^tm1Asil/Csnk1e^tm1.1Asil
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csnk1e^tm1.1Asil mutation (1 available); any Csnk1e mutation (31 available)
Csnk1e^tm1Asil mutation (1 available); any Csnk1e mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

shortened circadian behavior period ( J:135186 )

• significant shortening of circadian period identical to heterozygous Csnk1e^tm1Asil/Csnk1e⁺ mice

• 1.8 hr shorter circadian period than wild-type

• mutant mice are viable and fertile with no overt deleterious phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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