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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fgf16tm1(cre)Sms
targeted mutation 1, Suzanne L Mansour
MGI:3790778
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fgf16tm1(cre)Sms/Fgf16tm1(cre)Sms involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3810531
ot2
 		Fgf16tm1(cre)Sms/Y involves: 129S1/Sv * 129X1/SvJ MGI:3810533


Genotype
MGI:3810531
hm1
Allelic
Composition		 Fgf16tm1(cre)Sms/Fgf16tm1(cre)Sms
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf16tm1(cre)Sms mutation (0 available); any Fgf16 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:139718 )
N
• at weaning, homozygous female pups are present in the expected Mendelian numbers/ratio among progeny of heterozygous female by hemizygous male mice

reproductive system
reproductive system phenotype ( J:139718 )
N
• female mice homozygous for this mutation exhibit normal fertility

hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:139718 )
N
• homozygous mutant female mice do not exhibit behaviors indicating vestibular dysfunction, e.g., circling or head bobbing/shaking
• fixed, paint-filled inner ear structures of E15.5 homozygous female embryos exhibit no gross morphological abnormalities

behavior/neurological
behavior/neurological phenotype ( J:139718 )
N
• homozygous mutant female mice do not exhibit behaviors indicating vestibular dysfunction, e.g., circling or head bobbing/shaking




Genotype
MGI:3810533
ot2
Allelic
Composition		 Fgf16tm1(cre)Sms/Y
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf16tm1(cre)Sms mutation (0 available); any Fgf16 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:139718 )
N
• at weaning, hemizygous male pups are present at the expected Mendelian number/ratio among progeny of crosses between heterozygous female and hemizygous or wild-type male mice

reproductive system
reproductive system phenotype ( J:139718 )
N
• male mice hemizygous for this mutation exhibit normal fertility

hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:139718 )
N
• hemizygous mutant male mice do not exhibit behaviors indicating vestibular dysfunction, e.g., circling or head bobbing/shaking
• the ABR thresholds of hemizygous mutant males do not differ significantly from those of control heterozygous and wild-type female mice, averaging 29 dB vs. 28 dB and 29 dB, respectively
• fixed, paint-filled inner ear structures of E15.5 hemizygous male embryos exhibit no gross morphological abnormalities

behavior/neurological
behavior/neurological phenotype ( J:139718 )
N
• hemizygous mutant male mice do not exhibit behaviors indicating vestibular dysfunction, e.g., circling or head bobbing/shaking




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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory