Phenotypes associated with this allele

• Allele Symbol: Mboat4^tm1Jagu
• Allele Name: targeted mutation 1, Jesus A Gutierrez
• Allele ID: MGI:3790106
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mboat4^tm1Jagu/Mboat4^tm1Jagu	involves: C57BL/6	MGI:3797384

Genotype
MGI:3797384

hm1

• Allelic Composition: Mboat4^tm1Jagu/Mboat4^tm1Jagu
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal circulating ghrelin level ( J:151420 )

• only the inactive, des-acyl form of the hormone ghrelin is found in circulation

increased energy expenditure ( J:151420 )

• mice have increased energy expenditure when fed a diet rich in octanoic and decanoic acids

decreased susceptibility to diet-induced obesity ( J:151420 )

• mice fed a high-fat diet for 8 weeks have less weight gain than diet-matched controls

• mice also have less weight gain than controls when fed a diet rich in enhanced in octanoic and decanoic acids

• less weight gain is attributable to lower fat mass

adipose tissue

decreased total body fat amount ( J:151420 )

• fat mass is significantly less than controls when mice are fed a diet rich in octanoic and decanoic acids

behavior/neurological

increased food intake ( J:151420 )

• mice eat about 20% more then diet-matched controls when fed a diet rich in octanoic and decanoic acids

growth/size/body

decreased susceptibility to diet-induced obesity ( J:151420 )

• mice fed a high-fat diet for 8 weeks have less weight gain than diet-matched controls

• mice also have less weight gain than controls when fed a diet rich in enhanced in octanoic and decanoic acids

• less weight gain is attributable to lower fat mass