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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(CAG-IL1RN)1Cga
transgene insertion 1, Cem Gabay
MGI:3789047
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Apoetm1Unc/Apoetm1Unc
Tg(CAG-IL1RN)1Cga/?
involves: 129P2/OlaHsd * C57BL/6 * DBA/1 * FVB MGI:3789130


Genotype
MGI:3789130
cx1
Allelic
Composition
Apoetm1Unc/Apoetm1Unc
Tg(CAG-IL1RN)1Cga/?
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * DBA/1 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (33 available); any Apoe mutation (146 available)
Tg(CAG-IL1RN)1Cga mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• atherosclerotic lesions in the aortic root are reduced by 47% relative to Apoetm1Unc single homozygotes
• 53% reduction in the descending aorta
• reduced susceptibility in the aortic arch

immune system
• undetectable levels of serum Amyloid A

homeostasis/metabolism
• undetectable levels of serum Amyloid A





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory