Phenotypes associated with this allele

• Allele Symbol: Tgfbr2^tm1Dgen
• Allele Name: targeted mutation 1, Deltagen
• Allele ID: MGI:3785874
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Tgfbr2^tm1Dgen/Tgfbr2^+	involves: 129P2/OlaHsd	MGI:3848614

Genotype
MGI:3848614

ht1

• Allelic Composition: Tgfbr2^tm1Dgen/Tgfbr2⁺
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:148831 )

• males have a reduced fat/lean ratio (males show increased adiposity relative to females)

abnormal fat pad morphology ( J:148831 )

• males show a trend to decreased individual fat pad weights; females show the opposite (trend to higher fat pad weights relative to wild type)

homeostasis/metabolism

increased fatty acids level ( J:148831 )

• mice show significant increase in endpoint free fatty acids