All Phenotypes Myf5<tm1.1(cre)Mrc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Myf5^{tm1.1(cre)Mrc}
targeted mutation 1.1, Mario R Capecchi
MGI:3783303

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^tm1(DTA)Mrc/Gt(ROSA)26Sor⁺ Myf5^{tm1.1(cre)Mrc}/Myf5⁺	involves: 129S1/Sv * 129X1/SvJ	MGI:3783863

Allelic Composition	Gt(ROSA)26Sor^tm1(DTA)Mrc/Gt(ROSA)26Sor⁺ Myf5^{tm1.1(cre)Mrc}/Myf5⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm1(DTA)Mrc mutation (1 available); any Gt(ROSA)26Sor mutation (1046 available)
Myf5^{tm1.1(cre)Mrc} mutation (0 available); any Myf5 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:133338 )

• pups fail to survive after birth

muscle

muscle phenotype ( J:133338 )

N	• normal myogenesis • both fast and slow fibers with normal morphology • functional and utrastructural integrity normal

skeleton

abnormal rib morphology ( J:133338 )

• newborns with severely deformed ribs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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