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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Ttr-Hfe)1Nca
transgene insertion 1, Nancy C Andrews
MGI:3778909
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Hfetm2Nca/Hfetm2Nca
Tg(Ttr-Hfe)1Nca/0 		involves: 129S6/SvEvTac * C57BL/6 MGI:3783645


Genotype
MGI:3783645
cx1
Allelic
Composition		 Hfetm2Nca/Hfetm2Nca
Tg(Ttr-Hfe)1Nca/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hfetm2Nca mutation (1 available); any Hfe mutation (35 available)
Tg(Ttr-Hfe)1Nca mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system

homeostasis/metabolism
decreased circulating iron level ( J:133221 )
• decrease in serum transferrin iron saturation
decreased liver iron level ( J:133221 )
• decrease in stable liver iron compared to wild-type controls

liver/biliary system
decreased liver iron level ( J:133221 )
• decrease in stable liver iron compared to wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory