Phenotypes associated with this allele

• Allele Symbol: Slpi^tm1Ktak
• Allele Name: targeted mutation 1, Kiyoshi Takeda
• Allele ID: MGI:3778182
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slpi^tm1Ktak/Slpi^tm1Ktak	B6.129P2-Slpi^tm1Ktak	MGI:3809843

Genotype
MGI:3809843

hm1

• Allelic Composition: Slpi^tm1Ktak/Slpi^tm1Ktak
• Genetic Background: B6.129P2-Slpi^tm1Ktak

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to induced morbidity/mortality ( J:132933 )

• when infected intratracheally with M. tuberculosis all mice die within 8 weeks of infection while almost all wild-type mice survived for more than 9 weeks

immune system

increased susceptibility to bacterial infection ( J:132933 )

• highly susceptible to M. tuberculosis infection induced mortality when infected by the respiratory route of infection but not when infected intravenously