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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nek8+
wild type
MGI:3776500
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Nek8jck/Nek8+
Pkd1tm1Bdgz/Pkd1+ 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:3776501


Genotype
MGI:3776501
cx1
Allelic
Composition		 Nek8jck/Nek8+
Pkd1tm1Bdgz/Pkd1+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nek8jck mutation (1 available); any Nek8 mutation (28 available)
Pkd1tm1Bdgz mutation (0 available); any Pkd1 mutation (151 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
kidney cyst ( J:130086 )
• double heterozygous animals display increased frequency of cystogenesis at 16 weeks of age, compared to single heterozygotes for either gene

growth/size/body
kidney cyst ( J:130086 )
• double heterozygous animals display increased frequency of cystogenesis at 16 weeks of age, compared to single heterozygotes for either gene




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory