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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ldhaa-m7Neu
mutation 7, Neuherberg
MGI:3776295
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ldhaa-m7Neu/Ldhaa-m7Neu involves: 102/El * C3H/El MGI:5424180
ht2
 		Ldhaa-m7Neu/Ldha+ involves: 102/El * C3H/El MGI:5424182


Genotype
MGI:5424180
hm1
Allelic
Composition		 Ldhaa-m7Neu/Ldhaa-m7Neu
Genetic
Background		 involves: 102/El * C3H/El
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ldhaa-m7Neu mutation (0 available); any Ldha mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal enzyme/coenzyme activity ( J:65152 )
• homozygotes from mutant line LDH 1962 exhibits approximately 20% of wild-type enzyme activity in whole blood

mortality/aging
preweaning lethality, incomplete penetrance ( J:65152 )
• the number of homozygous mutants from the progeny of heterozygous inter se matings is less than expected




Genotype
MGI:5424182
ht2
Allelic
Composition		 Ldhaa-m7Neu/Ldha+
Genetic
Background		 involves: 102/El * C3H/El
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ldhaa-m7Neu mutation (0 available); any Ldha mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal enzyme/coenzyme activity ( J:65152 )
• heterozygotes from mutant line LDH 1962 exhibits approximately 60% of wild-type enzyme activity in whole blood




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory