Analysis Tools|
Allele Symbol Allele Name Allele ID |
Itih4tm1Mish targeted mutation 1, Lopa Mishra MGI:3775819 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• only 1 mouse in 25 developed a liver neoplasm compared to the 40% incidence rate observed in mice carrying just one null allele for Spnb2
• the lone tumor was about 10-fold smaller than the mean tumor sizes observed in the control mice
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• apoptosis rates are lower in hepatocytes compared to control mice
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• hepatocyte proliferation is lower than in controls
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• only 1 mouse in 25 developed a liver neoplasm compared to the 40% incidence rate observed in mice carrying just one null allele for Spnb2
• the lone tumor was about 10-fold smaller than the mean tumor sizes observed in the control mice
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• apoptosis rates are lower in hepatocytes compared to control mice
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• hepatocyte proliferation is lower than in controls
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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