Phenotypes associated with this allele

• Allele Symbol: Lsamp^tm1Afpi
• Allele Name: targeted mutation 1, Aurea Fugazzola Pimenta
• Allele ID: MGI:3773703
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lsamp^tm1Afpi/Lsamp^tm1Afpi	B6.129-Lsamp^tm1Afpi	MGI:3797602

Genotype
MGI:3797602

hm1

• Allelic Composition: Lsamp^tm1Afpi/Lsamp^tm1Afpi
• Genetic Background: B6.129-Lsamp^tm1Afpi

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased exploration in new environment ( J:131383 )

• mutants are hyperresponsive to novel environments

• mutants display hyperactivity in a novel open arena and although both sexes habituate to the same activity levels as wild-type, they do so at different rates

• in the elevated plus maze, mutants exhibit increases in open arm time, increases in open arm entries and increases in unprotected head-dips

• in the y-maze, mutants exhibit hyperactivity and a decrease in levels of spontaneous alternation during the period when their novelty-induced hyperactivity is at its peak