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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kcnq1ot1tm2Tilg
targeted mutation 2, Shirley M Tilghman
MGI:3773025
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Kcnq1ot1tm2Tilg/Kcnq1ot1+ involves: 129S1/Sv * C57BL/6 * M. spretus MGI:3773042
ht2
 		Kcnq1ot1tm2Tilg/Kcnq1ot1+ involves: 129S1/Sv * M. spretus MGI:4830276


Genotype
MGI:3773042
ht1
Allelic
Composition		 Kcnq1ot1tm2Tilg/Kcnq1ot1+
Genetic
Background		 involves: 129S1/Sv * C57BL/6 * M. spretus
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal imprinting ( J:108700 )
• paternal transmission of the deletion leads to the biallelic expression of several genes that are normally only expressed on the maternal allele




Genotype
MGI:4830276
ht2
Allelic
Composition		 Kcnq1ot1tm2Tilg/Kcnq1ot1+
Genetic
Background		 involves: 129S1/Sv * M. spretus
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal imprinting ( J:163857 )
• when this allele is inherited paternally, mice exhibit disruption in both ubiquitously and placental-specific imprinting compared with wild-type mice




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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory