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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gsk3atm1Jrw
targeted mutation 1, James R Woodgett
MGI:3771221
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		\Apctm1Tno/\Apctm1Tno
\Gsk3atm1Jrw/\Gsk3atm1Jrw
\Gsk3btm2Jrw/\Gsk3btm2Jrw 		involves: 129 * C57BL/6 * CBA MGI:4943266


Genotype
MGI:4943266
cn1
Allelic
Composition		 \Apctm1Tno/\Apctm1Tno
\Gsk3atm1Jrw/\Gsk3atm1Jrw
\Gsk3btm2Jrw/\Gsk3btm2Jrw
Genetic
Background		 involves: 129 * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm1Tno mutation (5 available); any Apc mutation (156 available)
Gsk3atm1Jrw mutation (0 available); any Gsk3a mutation (17 available)
Gsk3btm2Jrw mutation (2 available); any Gsk3b mutation (110 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
abnormal urinary bladder urothelium morphology ( J:164579 )
• mice develop hyperplastic lesions in the bladder unlike wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory