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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
malf
malformed ear
MGI:3770630
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
malf/malf CXB5/ByJ-malf/J MGI:5661936


Genotype
MGI:5661936
hm1
Allelic
Composition
malf/malf
Genetic
Background
CXB5/ByJ-malf/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
malf mutation (1 available); any malf mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

malf/malf mouse with one misplaced ear and a twisted snout

craniofacial
• some of the homozygotes with a misplaced or malformed ear also have assymmetry of the snout that can be a very noticeable twist
• ear pinnae can be smaller than normal or misshapen
• one or both ears can be positioned lower than normal and which ear is affected is not impacted by the phenotype of the parents
• of 37 mutants 28 had the left pinna affected, 8 had the right pinna affected and 1 had both affected

hearing/vestibular/ear
• ear pinnae can be smaller than normal or misshapen
• one or both ears can be positioned lower than normal and which ear is affected is not impacted by the phenotype of the parents
• of 37 mutants 28 had the left pinna affected, 8 had the right pinna affected and 1 had both affected

growth/size/body
• some of the homozygotes with a misplaced or malformed ear also have assymmetry of the snout that can be a very noticeable twist
• ear pinnae can be smaller than normal or misshapen
• one or both ears can be positioned lower than normal and which ear is affected is not impacted by the phenotype of the parents
• of 37 mutants 28 had the left pinna affected, 8 had the right pinna affected and 1 had both affected





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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory