All Phenotypes Csrnp2<tm1Jni> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Csrnp2^tm1Jni
targeted mutation 1, James N Ihle
MGI:3770131

Summary

5 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Csrnp2^tm1Jni/Csrnp2^tm1Jni	involves: 129P2/OlaHsd * C57BL/6	MGI:3770135
cx2	Csrnp3^tm1Jni/Csrnp3^tm1Jni Csrnp1^tm1Jni/Csrnp1⁺ Csrnp2^tm1Jni/Csrnp2^tm1Jni	involves: 129P2/OlaHsd * C57BL/6	MGI:3770137
cx3	Csrnp1^tm1Jni/Csrnp1^tm1Jni Csrnp2^tm1Jni/Csrnp2^tm1Jni	involves: 129P2/OlaHsd * C57BL/6	MGI:3770138
cx4	Csrnp3^tm1Jni/Csrnp3^tm1Jni Csrnp2^tm1Jni/Csrnp2^tm1Jni	involves: 129P2/OlaHsd * C57BL/6	MGI:3770139
cx5	Csrnp3^tm1Jni/Csrnp3^tm1Jni Csrnp1^tm1Jni/Csrnp1^tm1Jni Csrnp2^tm1Jni/Csrnp2^tm1Jni	involves: 129P2/OlaHsd * C57BL/6	MGI:3770140

Allelic Composition	Csrnp2^tm1Jni/Csrnp2^tm1Jni
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csrnp2^tm1Jni mutation (0 available); any Csrnp2 mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

embryo phenotype ( J:129366 )

N	• mice exhibit normal development, hematopoiesis and T cell function

hematopoietic system

hematopoietic system phenotype ( J:129366 )

N	• mice exhibit normal development, hematopoiesis and T cell function

immune system

immune system phenotype ( J:129366 )

N	• mice exhibit normal development, hematopoiesis and T cell function

Allelic Composition	Csrnp3^tm1Jni/Csrnp3^tm1Jni Csrnp1^tm1Jni/Csrnp1⁺ Csrnp2^tm1Jni/Csrnp2^tm1Jni
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csrnp1^tm1Jni mutation (0 available); any Csrnp1 mutation (36 available)
Csrnp2^tm1Jni mutation (0 available); any Csrnp2 mutation (19 available)
Csrnp3^tm1Jni mutation (0 available); any Csrnp3 mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:129366 )

• survival rates range between 25% and 45% of expected values

Allelic Composition	Csrnp1^tm1Jni/Csrnp1^tm1Jni Csrnp2^tm1Jni/Csrnp2^tm1Jni
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

embryo phenotype ( J:129366 )

N	• mice exhibit normal development, hematopoiesis and T cell function

hematopoietic system

hematopoietic system phenotype ( J:129366 )

N	• mice exhibit normal development, hematopoiesis and T cell function

immune system

immune system phenotype ( J:129366 )

N	• mice exhibit normal development, hematopoiesis and T cell function

Allelic Composition	Csrnp3^tm1Jni/Csrnp3^tm1Jni Csrnp2^tm1Jni/Csrnp2^tm1Jni
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csrnp2^tm1Jni mutation (0 available); any Csrnp2 mutation (19 available)
Csrnp3^tm1Jni mutation (0 available); any Csrnp3 mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:129366 )

• survival rates range between 25% and 45% of expected values

Allelic Composition	Csrnp3^tm1Jni/Csrnp3^tm1Jni Csrnp1^tm1Jni/Csrnp1^tm1Jni Csrnp2^tm1Jni/Csrnp2^tm1Jni
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality ( J:129366 )

• the majority of mice die within the first 48 hours after birth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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