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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Actbtm1Npa
targeted mutation 1, Novartis Pharma AG
MGI:3770046
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Actbtm1Npa/Actbtm1Npa involves: BALB/cJ MGI:3770048
ht2
 		Actbtm1Npa/Actb+ involves: BALB/cJ MGI:3770049


Genotype
MGI:3770048
hm1
Allelic
Composition		 Actbtm1Npa/Actbtm1Npa
Genetic
Background		 involves: BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Actbtm1Npa mutation (0 available); any Actb mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:129639 )
• embryos die between day E10.5 and E11.5




Genotype
MGI:3770049
ht2
Allelic
Composition		 Actbtm1Npa/Actb+
Genetic
Background		 involves: BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Actbtm1Npa mutation (0 available); any Actb mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:129639 )
• adults have 10% lower body weight




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory