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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Twist1tm2Bhr
targeted mutation 2, Richard R Behringer
MGI:3768516
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Twist1tm2Bhr/Twist1tm2Bhr involves: 129S7/SvEvBrd * C57BL/6J MGI:3768520
ht2
 		Twist1tm1Bhr/Twist1tm2Bhr involves: 129S7/SvEvBrd * C57BL/6J MGI:3768524


Genotype
MGI:3768520
hm1
Allelic
Composition		 Twist1tm2Bhr/Twist1tm2Bhr
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Twist1tm2Bhr mutation (1 available); any Twist1 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
skeleton phenotype ( J:128714 )
N
• mice do not exhibit any hindlimb polydactyly




Genotype
MGI:3768524
ht2
Allelic
Composition		 Twist1tm1Bhr/Twist1tm2Bhr
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Twist1tm1Bhr mutation (4 available); any Twist1 mutation (18 available)
Twist1tm2Bhr mutation (1 available); any Twist1 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
short temporal bone squamous part ( J:128714 )
• in all mice at E18.5

limbs/digits/tail
polydactyly ( J:128714 )
• at E18.5, 10 of 20 mice exhibit hindlimb polydactyly

skeleton
short temporal bone squamous part ( J:128714 )
• in all mice at E18.5




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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory