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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(CAG-STUB1)1Sobue
transgene insertion 1, Gen Sobue
MGI:3767714
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Tg(CAG-AR*97Q)7-8Sobue/?
Tg(CAG-STUB1)1Sobue/Tg(CAG-STUB1)1Sobue
involves: C57BL/6 * C57BL/6J * DBA/2 MGI:3767787
cx2
Tg(CAG-AR*97Q)7-8Sobue/?
Tg(CAG-STUB1)1Sobue/?
involves: C57BL/6 * C57BL/6J * DBA/2 MGI:3767788
tg3
Tg(CAG-STUB1)1Sobue/Tg(CAG-STUB1)1Sobue involves: C57BL/6 * DBA/2 MGI:3767786
tg4
Tg(CAG-STUB1)1Sobue/? involves: C57BL/6 * DBA/2 MGI:3767785


Genotype
MGI:3767787
cx1
Allelic
Composition
Tg(CAG-AR*97Q)7-8Sobue/?
Tg(CAG-STUB1)1Sobue/Tg(CAG-STUB1)1Sobue
Genetic
Background
involves: C57BL/6 * C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• motor coordination impairment on a rotarod test is not as sever as in Tg(ACTB-AR*97Q)2-6Sobu male mice but not as improved as in Tg(ACTB-STUB1)Sobu/Tg(ACTB-STUB1)Sobu Tg(ACTB-AR*97Q)2-6Sobu male mice
• male mice took smaller steps when walking than Tg(ACTB-STUB1)Sobu/Tg(ACTB-STUB1)Sobu Tg(ACTB-AR*97Q)2-6Sobu male but longer than Tg(ACTB-AR*97Q)2-6Sobu male mice

muscle
• muscular atrophy in male mice is less than in Tg(ACTB-AR*97Q)2-6Sobu male mice

growth/size/body
• male mice do not lose as much weight as quickly as Tg(ACTB-AR*97Q)2-6Sobu mice




Genotype
MGI:3767788
cx2
Allelic
Composition
Tg(CAG-AR*97Q)7-8Sobue/?
Tg(CAG-STUB1)1Sobue/?
Genetic
Background
involves: C57BL/6 * C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• motor coordination impairment on a rotarod test is not as sever as in Tg(ACTB-AR*97Q)2-6Sobu male mice or Tg(ACTB-STUB1)Sobu Tg(ACTB-AR*97Q)2-6Sobu male mice and begins at 16 weeks
• however, mice walk normally

growth/size/body
• male mice do not lose as much weight as quickly as Tg(ACTB-AR*97Q)2-6Sobu male mice




Genotype
MGI:3767786
tg3
Allelic
Composition
Tg(CAG-STUB1)1Sobue/Tg(CAG-STUB1)1Sobue
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• male mice up to 50 weeks of age display no motor coordination impairments in a rotarod test
• male mice display a slight delay in weaning

muscle
N
• male mice possess normal muscular structure

nervous system
N
• male mice display normal neuronal cell morphology and number




Genotype
MGI:3767785
tg4
Allelic
Composition
Tg(CAG-STUB1)1Sobue/?
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• male mice up to 50 weeks of age display no motor coordination impairments in a rotarod test
• male mice display a slight delay in weaning

muscle
N
• male mice possess normal muscular structure

nervous system
N
• male mice display normal neuronal cell morphology and number





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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory