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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fbxw7tm1.1Kei
targeted mutation 1.1, Keiichi Nakayama
MGI:3767578
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fbxw7tm1.1Kei/Fbxw7tm1.1Kei involves: 129P2/OlaHsd * C57BL/6 MGI:3767594


Genotype
MGI:3767594
hm1
Allelic
Composition		 Fbxw7tm1.1Kei/Fbxw7tm1.1Kei
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxw7tm1.1Kei mutation (0 available); any Fbxw7 mutation (81 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:128523 )
• mice die in utero and none are recovered at birth

cardiovascular system
abnormal vascular development ( J:128523 )
• mice are indistinguishable from Fbxw7tm1Kin homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory