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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Myh6/tetO-BNIP3)1Gwd
transgene insertion 1, Gerald W Dorn II
MGI:3764670
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Tg(Myh6-tTA)55Rbns/?
Tg(Myh6/tetO-BNIP3)1Gwd/?
Not Specified MGI:3764675


Genotype
MGI:3764675
cx1
Allelic
Composition
Tg(Myh6-tTA)55Rbns/?
Tg(Myh6/tetO-BNIP3)1Gwd/?
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Myh6/tetO-BNIP3)1Gwd mutation (0 available)
Tg(Myh6-tTA)55Rbns mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• when expression begins neonatally, heart weight is increased (8.7+/-0.9 mg/g compared to 5.7+/-0.3 mg/g in wild-type mice)
• whether expression begins neonatally or at 8 weeks of age, neonates develop progressive left ventricle dilation that is not as severe in adulthood
• whether expression begins neonatally or at 8 weeks of age, left ventricle systolic pressure is decreased compared to in wild-type mice
• whether expression begins neonatally or at 8 weeks of age, apoptotic rate in the heart is increased 5- to 10-fold at 10 or 40 weeks of age
• whether expression begins neonatally or at 8 weeks of age, infarct size is larger than in wild-type mice

muscle
• whether expression begins neonatally or at 8 weeks of age, apoptotic rate in the heart is increased 5- to 10-fold at 10 or 40 weeks of age

homeostasis/metabolism
• whether expression begins neonatally or at 8 weeks of age, infarct size is larger than in wild-type mice

cellular
• whether expression begins neonatally or at 8 weeks of age, apoptotic rate in the heart is increased 5- to 10-fold at 10 or 40 weeks of age

growth/size/body
• when expression begins neonatally, heart weight is increased (8.7+/-0.9 mg/g compared to 5.7+/-0.3 mg/g in wild-type mice)





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory