Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prnptm4(PRNP)Tkit mutation
(0 available);
any
Prnp mutation
(150 available)
|
|
|
immune system
|
• mice are highly susceptible to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob prion infection
• however, mice are not susceptible to sporadic prion infection
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prnptm4(PRNP)Tkit mutation
(0 available);
any
Prnp mutation
(150 available)
Tg(Prnp-PRNP)32Tkit mutation
(0 available)
|
|
|
immune system
|
• mice are highly susceptible to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob prion infection
• however, mice are not susceptible to sporadic or dura graft-associated prion infection
|