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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Psmd4tm2.1Smta
targeted mutation 2.1, Shigeo Murata
MGI:3762171
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Psmd4tm2.1Smta/Psmd4tm2.1Smta involves: C57BL/6 * CBA * FVB/N MGI:3762175
ht2
 		Psmd4tm2.1Smta/Psmd4+ involves: C57BL/6 * CBA * FVB/N MGI:3762179


Genotype
MGI:3762175
hm1
Allelic
Composition		 Psmd4tm2.1Smta/Psmd4tm2.1Smta
Genetic
Background		 involves: C57BL/6 * CBA * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Psmd4tm2.1Smta mutation (0 available); any Psmd4 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:126546 )
• mice cease to develop at E8.5

embryo
embryonic growth retardation ( J:126546 )
• at E9.5 mice resemble those at E8.5

growth/size/body
embryonic growth retardation ( J:126546 )
• at E9.5 mice resemble those at E8.5




Genotype
MGI:3762179
ht2
Allelic
Composition		 Psmd4tm2.1Smta/Psmd4+
Genetic
Background		 involves: C57BL/6 * CBA * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Psmd4tm2.1Smta mutation (0 available); any Psmd4 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
postnatal growth retardation ( J:126546 )
• mice exhibit slightly retarded growth and maturation
• however, mice are otherwise normal




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory