All Phenotypes Scp2<tm1Fsch> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Scp2^tm1Fsch
targeted mutation 1, Friedhelm Schroeder
MGI:3762148

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Scp2^tm1Fsch/Scp2^tm1Fsch	B6.129P2-Scp2^tm1Fsch	MGI:3762149

Allelic Composition	Scp2^tm1Fsch/Scp2^tm1Fsch
Genetic Background	B6.129P2-Scp2^tm1Fsch

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scp2^tm1Fsch mutation (2 available); any Scp2 mutation (59 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

liver/biliary system

abnormal hepatocyte morphology ( J:126573 )

• cultured of primary hepatocytes display altered lipid rafts with an increase in the proportion of lipid rafts present, an increase in total phospholipids and decrease in GM1 in lipid rafts, and a decrease in lipid raft fluidity

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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