All Phenotypes Plpp3<tm2Stw> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Plpp3^tm2Stw
targeted mutation 2, Colin L Stewart
MGI:3723646

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plpp3^tm2Stw/Plpp3^tm2Stw	involves: 129S1/Sv * C57BL/6J	MGI:3826989

Allelic Composition	Plpp3^tm2Stw/Plpp3^tm2Stw
Genetic Background	involves: 129S1/Sv * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plpp3^tm2Stw mutation (0 available); any Plpp3 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality ( J:142493 )

embryo

abnormal gastrulation ( J:142493 )

• low penetrance of gastrulation defects

embryonic growth retardation ( J:142493 )

• developmental delay of about 12 to 24 hours

open neural tube ( J:142493 )

• frequently seen in the best developed embryos

abnormal allantois morphology ( J:142493 )

• allantois compaction

failure of chorioallantoic fusion ( J:142493 )

• absence of fusion at the 6 somite stage

• impaired remodeling of the primary vascular plexus

nervous system

open neural tube ( J:142493 )

• frequently seen in the best developed embryos

growth/size/body

embryonic growth retardation ( J:142493 )

• developmental delay of about 12 to 24 hours

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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