About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Vmn2r81tm2Mom
targeted mutation 2, Peter Mombaerts
MGI:3722385
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Vmn2r81tm2Mom/Vmn2r81tm2Mom B6;129P2-Vmn2r81tm2Mom/MomJ MGI:4850117
cx2
 		Del(17)5Mom/Del(17)5Mom
Vmn2r81tm2Mom/Vmn2r81tm2Mom 		involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd MGI:5564785


Genotype
MGI:4850117
hm1
Allelic
Composition		 Vmn2r81tm2Mom/Vmn2r81tm2Mom
Genetic
Background		 B6;129P2-Vmn2r81tm2Mom/MomJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vmn2r81tm2Mom mutation (1 available); any Vmn2r81 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:5564785
cx2
Allelic
Composition		 Del(17)5Mom/Del(17)5Mom
Vmn2r81tm2Mom/Vmn2r81tm2Mom
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(17)5Mom mutation (2 available); any Del(17)5Mom mutation (2 available)
Vmn2r81tm2Mom mutation (1 available); any Vmn2r81 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:207447 )
N
• normal presynaptic terminal around vomeronasal sensory neuron glomeruli
abnormal vomeronasal sensory neuron physiology ( J:207447 )
• higher concentrations of VMR2R81 specific MHC peptides are required to induce calcium responses; however, maximum response remains the same

respiratory system

craniofacial

growth/size/body
abnormal vomeronasal sensory neuron morphology ( J:207447 )
• smaller glomeruli




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory