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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pvrtm1Gbn
targeted mutation 1, Gunter Bernhardt
MGI:3719436
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pvrtm1Gbn/Pvrtm1Gbn either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * BALB/c) MGI:3720624


Genotype
MGI:3720624
hm1
Allelic
Composition		 Pvrtm1Gbn/Pvrtm1Gbn
Genetic
Background		 either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * BALB/c)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pvrtm1Gbn mutation (2 available); any Pvr mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgA level ( J:123540 )
• following oral immunization with cholera toxin, IgA levels are decreased relative to wild-type mice
decreased IgG level ( J:123540 )
• following oral immunization with cholera toxin, IgG1, IgG2a and IgG2b levels are decreased relative to wild-type mice
abnormal response to infection ( J:123540 )
• following oral immunization with cholera toxin, IgA, IgG1, IgG2a and IgG2b levels are decreased relative to wild-type mice

hematopoietic system
decreased IgA level ( J:123540 )
• following oral immunization with cholera toxin, IgA levels are decreased relative to wild-type mice
decreased IgG level ( J:123540 )
• following oral immunization with cholera toxin, IgG1, IgG2a and IgG2b levels are decreased relative to wild-type mice




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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory