All Phenotypes Mef2d<tm1.1Eno> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mef2d^tm1.1Eno
targeted mutation 1.1, Eric N Olson
MGI:3718328

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Mef2c^tm1Eno/Mef2c⁺ Mef2d^tm1.1Eno/Mef2d⁺	involves: 129S7/SvEvBrd	MGI:3719007

Allelic Composition	Mef2c^tm1Eno/Mef2c⁺ Mef2d^tm1.1Eno/Mef2d⁺
Genetic Background	involves: 129S7/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mef2c^tm1Eno mutation (0 available); any Mef2c mutation (36 available)
Mef2d^tm1.1Eno mutation (0 available); any Mef2d mutation (63 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:119152 )

• die within a day after birth

skeleton

failure of sternum ossification ( J:119152 )

• the lack of ossification in the sternum is more severe than in single Mef2c^tm1Eno heterozygotes

• exhibit almost no hypertrophic chondrocytes in the sternum

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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