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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
hlb349A
heart, lung and blood, 349A
MGI:3718207
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
hlb349A/hlb349A involves: 129S1/SvImJ * C57BL/6J MGI:3718213


Genotype
MGI:3718213
hm1
Allelic
Composition
hlb349A/hlb349A
Genetic
Background
involves: 129S1/SvImJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
hlb349A mutation (1 available); any hlb349A mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• after consuming an atherogenic diet for 3 weeks, a 12 week-old homozygous mutant mouse had a percent body fat of 22.38; female mutants become more obese than males on this regimen

growth/size/body
• 12 week-old homozygous mutants fed an atherogenic diet for 3 weeks become obese, one animal weighing 30.71 g and having a percent body fat of 22.38; females are more severely affected than are males
• the weight gain of 12 week-old homozygous mutant mice during 3 weeks on an atherogenic diet is greater than that of normal controls; the difference is greater for female than for male mice

homeostasis/metabolism
• the weight gain of 12 week-old homozygous mutant mice during 3 weeks on an atherogenic diet is greater than that of normal controls; the difference is greater for female than for male mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory