About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cacna1atm1(CACNA1A)Ttan
targeted mutation 1, Tsutomu Tanabe
MGI:3718032
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cacna1atm1(CACNA1A)Ttan/Cacna1atm1(CACNA1A)Ttan involves: 129S4/SvJae MGI:3718373
ht2
Cacna1atm1(CACNA1A)Ttan/Cacna1a+ involves: 129S4/SvJae MGI:3718377


Genotype
MGI:3718373
hm1
Allelic
Composition
Cacna1atm1(CACNA1A)Ttan/Cacna1atm1(CACNA1A)Ttan
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacna1atm1(CACNA1A)Ttan mutation (0 available); any Cacna1a mutation (115 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice die around 3 weeks after birth

behavior/neurological
• severe

muscle




Genotype
MGI:3718377
ht2
Allelic
Composition
Cacna1atm1(CACNA1A)Ttan/Cacna1a+
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacna1atm1(CACNA1A)Ttan mutation (0 available); any Cacna1a mutation (115 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• at 6 and 12 months of age, mice exhibit a shortened latency to call compared to wild-type mice
• however, at 6 and 9 months of age, mice exhibit longer retention time compared to wild-type mice and other measures of coordination are normal





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory