About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trpm8tm1Jul
targeted mutation 1, David Julius
MGI:3716518
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Trpm8tm1Jul/Trpm8tm1Jul involves: 129P2/OlaHsd * C57BL/6 MGI:3717466


Genotype
MGI:3717466
hm1
Allelic
Composition		 Trpm8tm1Jul/Trpm8tm1Jul
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trpm8tm1Jul mutation (1 available); any Trpm8 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal thermosensation ( J:122978 )
• mice have no preference for a room temperature surface over a cold surface as wild-type mice do
increased thermal nociceptive threshold ( J:122978 )
• mice respond less to cold stimuli




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory