Analysis Tools
growth/size/body
|
• slightly lower body weight over the first 7 weeks of postnatal development
(J:122391)
• male, but not female, body weight is on average 10% lower than in wild-type, mostly due to the decrease in skeletal muscle mass
(J:123052)
|
muscle
|
• cardiac muscle mass is 17.1% lower in males but not in females at 7 weeks of age
|
|
• the mean gastrocnemius muscle fiber cross-sectional area is 18% lower in males than in wild-type
• the number of myonuclei in gastrocnemius muscle is lower in males than in wild-type
|
|
• the mean gastrocnemius muscle fiber cross-sectional area is 18% lower in males than in wild-type
|
|
• males, but not females, display a 20-22% reduction it the skeletal muscle mass of the gastrocnemius, quadriceps, and tibialis anterior muscles at 7 weeks of age
• males exhibit 25.8% and 17.6% lower muscle mass of biceps and forearm, respectively
|
cardiovascular system
|
• cardiac muscle mass is 17.1% lower in males but not in females at 7 weeks of age
|
|
• heart weights in males are 11% lower than in wild-type
|
|
• left ventricular mass is 21% lower than in wild-type
• however, ejection fraction does not differ from wild-type
|
adipose tissue
|
• mean weights of the epididymal fat pad are higher than in wild-type
• however, observe no differences in parametrial fat weight in females
|
