About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Dvl2/EGFP)2Awb
transgene insertion 2, Anthony Wynshaw-Boris
MGI:3715908
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Dvl1tm1Awb/Dvl1tm1Awb
Dvl2tm1Awb/Dvl2tm1Awb
Tg(Dvl2/EGFP)2Awb/? 		involves: 129S6/SvEvTac MGI:3715989
cx2
 		Dvl2tm1Awb/Dvl2tm1Awb
Tg(Dvl2/EGFP)2Awb/?
Vangl2Lp/Vangl2+ 		involves: 129S6/SvEvTac * LPT/LeJ MGI:3715990
cx3
 		Vangl2Lp/Vangl2Lp
Tg(Dvl2/EGFP)2Awb/? 		involves: LPT/LeJ MGI:3608681


Genotype
MGI:3715989
cx1
Allelic
Composition		 Dvl1tm1Awb/Dvl1tm1Awb
Dvl2tm1Awb/Dvl2tm1Awb
Tg(Dvl2/EGFP)2Awb/?
Genetic
Background		 involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dvl1tm1Awb mutation (2 available); any Dvl1 mutation (35 available)
Dvl2tm1Awb mutation (1 available); any Dvl2 mutation (33 available)
Tg(Dvl2/EGFP)2Awb mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:108512 )
• mice are restored to fertile adults




Genotype
MGI:3715990
cx2
Allelic
Composition		 Dvl2tm1Awb/Dvl2tm1Awb
Tg(Dvl2/EGFP)2Awb/?
Vangl2Lp/Vangl2+
Genetic
Background		 involves: 129S6/SvEvTac * LPT/LeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dvl2tm1Awb mutation (1 available); any Dvl2 mutation (33 available)
Tg(Dvl2/EGFP)2Awb mutation (0 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:108512 )
• mice are restored to fertile adults




Genotype
MGI:3608681
cx3
Allelic
Composition		 Vangl2Lp/Vangl2Lp
Tg(Dvl2/EGFP)2Awb/?
Genetic
Background		 involves: LPT/LeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Dvl2/EGFP)2Awb mutation (0 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
abnormal organ of Corti morphology ( J:100861 )
• at E18.5 the polarized subcellular distribution of Dvl2 driven GFP expression in the differentiating organ of Corti is disrupted




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory