All Phenotypes Cryge<No3> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cryge^No3
nuclear opacity 3
MGI:3713105

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cryge^No3/Cryge^No3	involves: 102/El * C3H/HeH	MGI:3713236
ht2	Cryge^No3/Cryge⁺	involves: 102/El * C3H/HeH	MGI:3713234
ht3	Cryge^No3/Cryge⁺	involves: 102/El * C3H/HeH * C57BL/6	MGI:3713235

Allelic Composition	Cryge^No3/Cryge^No3
Genetic Background	involves: 102/El * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cryge^No3 mutation (2 available); any Cryge mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

cataract ( J:121863 )

• all homozygous mice have cataracts, showing a more severe lens phenotype than heterozygotes

Allelic Composition	Cryge^No3/Cryge⁺
Genetic Background	involves: 102/El * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cryge^No3 mutation (2 available); any Cryge mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

nuclear cataract ( J:121863 )

• all affected animals show a visible nuclear opacity

• Background Sensitivity: when heterozygous animals are derived from crosses to C3H/HeH mice, 53% of animals are affected by cataracts, showing mild diffuse opacities in the lens nucleus; when homozygous mutants are crossed to C3H/HeH mice, essentially all (98.2%) mice show the mild phenotype

Allelic Composition	Cryge^No3/Cryge⁺
Genetic Background	involves: 102/El * C3H/HeH * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cryge^No3 mutation (2 available); any Cryge mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

cataract ( J:121863 )

• Background Sensitivity: when heterozygous animals are derived from crosses to C57BL/6 mice, only 28.5% of animals are affected by cataracts, showing mild diffuse opacities in the lens nucleus; this is likely due to incomplete penetrance of this phenotype on this background

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