About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Engtm2.2Hma
targeted mutation 2.2, Helen M Arthur
MGI:3712803
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Engtm2.2Hma/Engtm2.2Hma involves: 129P2/OlaHsd * BALB/c * C57BL/6 MGI:3712890


Genotype
MGI:3712890
hm1
Allelic
Composition
Engtm2.2Hma/Engtm2.2Hma
Genetic
Background
involves: 129P2/OlaHsd * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Engtm2.2Hma mutation (0 available); any Eng mutation (41 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• similar numbers of homozygotes and wild-type embryos are seen at 9.5 dpc, but no homozygotes are born alive

embryo
• at 9.5 dpc, angiogenesis defects in yolk sac are observed, contrasting to normal yolk sac of wild-type embryos
• authors state than embryos die mid-embryogenesis with phenotype indistinguishable from Engtm1Hma homozygotes

cardiovascular system
• at 9.5 dpc, angiogenesis defects in yolk sac are observed, contrasting to normal yolk sac of wild-type embryos





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory