About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Idd6.2C3H/HeJ
C3H/HeJ
MGI:3711830
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Idd6.2C3H/HeJ/Idd6.2C3H/HeJ involves: C3H/HeJ * NOD MGI:3711834
hm2
 		Idd6.2C3H/HeJ/Idd6.2C3H/HeJ NOD.C3-Idd6.2C3H/HeJ MGI:3804872


Genotype
MGI:3711834
hm1
Allelic
Composition		 Idd6.2C3H/HeJ/Idd6.2C3H/HeJ
Genetic
Background		 involves: C3H/HeJ * NOD
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to autoimmune diabetes ( J:115021 )
• decreased type 1 diabetes incidence




Genotype
MGI:3804872
hm2
Allelic
Composition		 Idd6.2C3H/HeJ/Idd6.2C3H/HeJ
Genetic
Background		 NOD.C3-Idd6.2C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased NK cell number ( J:137837 )
• decreased numbers of invariant natural killer (iNKT) cells in thymus compared to NOD mice
• decreased CD4+/double negative iNTK ratios compared to NOD mice
• decreased CD4+ iNKT cell numbers compared to NOD mice

immune system
decreased NK cell number ( J:137837 )
• decreased numbers of invariant natural killer (iNKT) cells in thymus compared to NOD mice
• decreased CD4+/double negative iNTK ratios compared to NOD mice
• decreased CD4+ iNKT cell numbers compared to NOD mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory