Phenotypes associated with this allele

• Allele Symbol: Gt(ROSA)26Sor^{tm1(Mirn155)Rsky}
• Allele Name: targeted mutation 1, Klaus Rajewsky
• Allele ID: MGI:3709879
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gt(ROSA)26Sor^tm1(Mirn155)Rsky/Gt(ROSA)26Sor^tm1(Mirn155)Rsky	involves: BALB/c * C57BL/6	MGI:3712187

Genotype
MGI:3712187

hm1

• Allelic Composition: Gt(ROSA)26Sor^{tm1(Mirn155)Rsky}/Gt(ROSA)26Sor^{tm1(Mirn155)Rsky}
• Genetic Background: involves: BALB/c * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:121084 )

N • mice are fertile

immune system

increased germinal center B cell number ( J:121084 )

• splenic germinal center, mesenteric lymph node germinal center and Peyer's patch germinal center B cell numbers are higher than in wild-type mice in response to NP-CGG

abnormal humoral immune response ( J:121084 )

• marginal enhancement in the antibody response to NP-CGG

hematopoietic system

increased germinal center B cell number ( J:121084 )

• splenic germinal center, mesenteric lymph node germinal center and Peyer's patch germinal center B cell numbers are higher than in wild-type mice in response to NP-CGG