About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1(Mirn155)Rsky
targeted mutation 1, Klaus Rajewsky
MGI:3709879
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gt(ROSA)26Sortm1(Mirn155)Rsky/Gt(ROSA)26Sortm1(Mirn155)Rsky involves: BALB/c * C57BL/6 MGI:3712187


Genotype
MGI:3712187
hm1
Allelic
Composition		 Gt(ROSA)26Sortm1(Mirn155)Rsky/Gt(ROSA)26Sortm1(Mirn155)Rsky
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Mirn155)Rsky mutation (0 available); any Gt(ROSA)26Sor mutation (1046 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:121084 )
N
• mice are fertile

immune system
increased germinal center B cell number ( J:121084 )
• splenic germinal center, mesenteric lymph node germinal center and Peyer's patch germinal center B cell numbers are higher than in wild-type mice in response to NP-CGG
abnormal humoral immune response ( J:121084 )
• marginal enhancement in the antibody response to NP-CGG

hematopoietic system
increased germinal center B cell number ( J:121084 )
• splenic germinal center, mesenteric lymph node germinal center and Peyer's patch germinal center B cell numbers are higher than in wild-type mice in response to NP-CGG




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory