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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sicd1C57BL/6J
C57BL/6J
MGI:3706137
Summary 3 genotypes


Genotype
MGI:3716504
hm1
Allelic
Composition		 Sicd1C57BL/6J/Sicd1C57BL/6J
Genetic
Background		 FVB.B6-(D18Mit129-D18Mit25)
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
loss of hippocampal neurons ( J:122922 )
• 75% reduction in kainic acid-induced hippocampal cell death, especially in area CA3, compared to FVB/NJ




Genotype
MGI:3716503
hm2
Allelic
Composition		 Sicd1C57BL/6J/Sicd1C57BL/6J
Genetic
Background		 FVB.B6-(D18Mit141-D18Mit25)
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
increased susceptibility to pharmacologically induced seizures ( J:122922 )
• decreased seizure latency induced by kainic acid
loss of hippocampal neurons ( J:122922 )
• resistance to neuronal cell death, especially in area CA3, after kainic acid-induced seizure

behavior/neurological
increased susceptibility to pharmacologically induced seizures ( J:122922 )
• decreased seizure latency induced by kainic acid




Genotype
MGI:3706140
hm3
Allelic
Composition		 Sicd1C57BL/6J/Sicd1C57BL/6J
Genetic
Background		 FVB.B6-(D18Mit186-D18Mit4)
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
loss of hippocampal neurons ( J:119634 )
• resistance to hippocampal cell death after kainic acid-induced seizure




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory