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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(KRT14-MAP2K1/Esr1)12Pkha
transgene insertion 12, Paul A Khavari
MGI:3700387
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(KRT14-MAP2K1/Esr1)12Pkha/0 involves: FVB MGI:3700843


Genotype
MGI:3700843
tg1
Allelic
Composition
Tg(KRT14-MAP2K1/Esr1)12Pkha/0
Genetic
Background
involves: FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(KRT14-MAP2K1/Esr1)12Pkha mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• topical application of 4-hydroxy-testosterone (4OHT) results in development of epidermal hyperplasia after 5 days; this remains stable after a further month of treatment, and is reversed upon cessation of 4OHT treatment





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory