Phenotypes associated with this allele

• Allele Symbol: Limd1^tm1Gdl
• Allele Name: targeted mutation 1, Gregory D Longmore
• Allele ID: MGI:3699087
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Limd1^tm1Gdl/Limd1^tm1Gdl	involves: 129X1/SvJ	MGI:3701296

Genotype
MGI:3701296

hm1

• Allelic Composition: Limd1^tm1Gdl/Limd1^tm1Gdl
• Genetic Background: involves: 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal osteoclast cell number ( J:118130 )

• in response to osteoclastogenic stimuli, numbers of osteoclasts (OC) do not increase whereas wild-type OCs increase significantly

abnormal osteoclast physiology ( J:118130 )

• mice are resistant to pathologic osteoclastogenic response to arthritis induction by injection of K/BxN serum

immune system

abnormal osteoclast cell number ( J:118130 )

• in response to osteoclastogenic stimuli, numbers of osteoclasts (OC) do not increase whereas wild-type OCs increase significantly

abnormal macrophage physiology ( J:118130 )

abnormal osteoclast physiology ( J:118130 )

• mice are resistant to pathologic osteoclastogenic response to arthritis induction by injection of K/BxN serum

hematopoietic system

abnormal osteoclast cell number ( J:118130 )

• in response to osteoclastogenic stimuli, numbers of osteoclasts (OC) do not increase whereas wild-type OCs increase significantly

abnormal macrophage physiology ( J:118130 )

abnormal osteoclast physiology ( J:118130 )

• mice are resistant to pathologic osteoclastogenic response to arthritis induction by injection of K/BxN serum