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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Agertm1Arnd
targeted mutation 1, Bernd Arnold
MGI:3698956
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Agertm1Arnd/Ager+ involves: 129P2/OlaHsd MGI:3698959
cn2
Agertm1Arnd/Ager+
Tg(Itgax-EGFP,-cre,-HBEGF,-luc)2Gjh/0
involves: 129P2/OlaHsd * C57BL/6 MGI:5476625


Genotype
MGI:3698959
ht1
Allelic
Composition
Agertm1Arnd/Ager+
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agertm1Arnd mutation (0 available); any Ager mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:5476625
cn2
Allelic
Composition
Agertm1Arnd/Ager+
Tg(Itgax-EGFP,-cre,-HBEGF,-luc)2Gjh/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agertm1Arnd mutation (0 available); any Ager mutation (28 available)
Tg(Itgax-EGFP,-cre,-HBEGF,-luc)2Gjh mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• depletion of conventional dendritic cells after treatment with diphtheria toxin is efficient with over 90% depletion
• depletion is less effective than for conventional cells (about 50%)

hematopoietic system
• depletion of conventional dendritic cells after treatment with diphtheria toxin is efficient with over 90% depletion
• depletion is less effective than for conventional cells (about 50%)





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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory