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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Camk2a-cre)20Kmik
transgene insertion 20, Katsuhiko Mikoshiba
MGI:3697168
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Prox1tm1.1Fuma/Prox1tm1.1Fuma
Tg(Camk2a-cre)20Kmik/0 		involves: C57BL/6NCrlj * CBA/JNCrlj MGI:5438958


Genotype
MGI:5438958
cn1
Allelic
Composition		 Prox1tm1.1Fuma/Prox1tm1.1Fuma
Tg(Camk2a-cre)20Kmik/0
Genetic
Background		 involves: C57BL/6NCrlj * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prox1tm1.1Fuma mutation (0 available); any Prox1 mutation (43 available)
Tg(Camk2a-cre)20Kmik mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dentate gyrus morphology ( J:187615 )
• the dentate gyrus is small due to apoptosis from leaky cre expression
• the dentate gyrus consists completely of CA3 pyramidal cells with no granule cells
abnormal hippocampus CA4 region morphology ( J:187615 )
• at P28, mossy cells are reduced in the hilus compared to in control mice
abnormal hippocampus granule cell morphology ( J:187615 )
• the dentate gyrus consists completely of CA3 pyramidal cells with no granule cells




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory