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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Myh6-Camta2)1Eno
transgene insertion 1, Eric N Olson
MGI:3696706
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Hdac5tm1Eno/Hdac5tm1Eno
Tg(Myh6-Camta2)1Eno/0
involves: 129S2/SvPas MGI:3696715
tg2
Tg(Myh6-Camta2)1Eno/0 Not Specified MGI:3696709


Genotype
MGI:3696715
cx1
Allelic
Composition
Hdac5tm1Eno/Hdac5tm1Eno
Tg(Myh6-Camta2)1Eno/0
Genetic
Background
involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hdac5tm1Eno mutation (0 available); any Hdac5 mutation (56 available)
Tg(Myh6-Camta2)1Eno mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• exhibit even more enhanced cardiac hypertrophy (twice the amount) than single transgenic Tg(Myh6-Camta2)1Eno mice

growth/size/body
• exhibit even more enhanced cardiac hypertrophy (twice the amount) than single transgenic Tg(Myh6-Camta2)1Eno mice




Genotype
MGI:3696709
tg2
Allelic
Composition
Tg(Myh6-Camta2)1Eno/0
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• all die by 12 weeks of age due to heart failure

cardiovascular system
• hearts show extensive myocyte hypertrophy; hypertrophy worsens between 4 and 8 weeks of age
• by 9 weeks of age, hypertrophy progresses to dilated cardiomyopathy
• by 9 weeks of age, hypertrophy progresses to heart failure

muscle
• by 9 weeks of age, hypertrophy progresses to dilated cardiomyopathy

growth/size/body
• hearts show extensive myocyte hypertrophy; hypertrophy worsens between 4 and 8 weeks of age





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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory