Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hdac5tm1Eno mutation
(0 available);
any
Hdac5 mutation
(56 available)
Tg(Myh6-Camta2)1Eno mutation
(0 available)
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cardiovascular system
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• exhibit even more enhanced cardiac hypertrophy (twice the amount) than single transgenic Tg(Myh6-Camta2)1Eno mice
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growth/size/body
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• exhibit even more enhanced cardiac hypertrophy (twice the amount) than single transgenic Tg(Myh6-Camta2)1Eno mice
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
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mortality/aging
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• all die by 12 weeks of age due to heart failure
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cardiovascular system
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• hearts show extensive myocyte hypertrophy; hypertrophy worsens between 4 and 8 weeks of age
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• by 9 weeks of age, hypertrophy progresses to dilated cardiomyopathy
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• by 9 weeks of age, hypertrophy progresses to heart failure
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muscle
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• by 9 weeks of age, hypertrophy progresses to dilated cardiomyopathy
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growth/size/body
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• hearts show extensive myocyte hypertrophy; hypertrophy worsens between 4 and 8 weeks of age
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