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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Igkj1tm1(IgkHyHEL10)Mnz
targeted mutation 1, Michel C Nussenzweig
MGI:3694788
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Igh-Jtm1(Ighel)Cys/Igh-Jtm1(Ighel)Cys
Myd88tm1Aki/Myd88tm1Aki
Igkj1tm1(IgkHyHEL10)Mnz/0 		involves: 129P2/OlaHsd MGI:3694812


Genotype
MGI:3694812
cx1
Allelic
Composition		 Igh-Jtm1(Ighel)Cys/Igh-Jtm1(Ighel)Cys
Myd88tm1Aki/Myd88tm1Aki
Igkj1tm1(IgkHyHEL10)Mnz/0
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igh-Jtm1(Ighel)Cys mutation (0 available); any Igh-J mutation (12 available)
Igkj1tm1(IgkHyHEL10)Mnz mutation (2 available); any Igkj1 mutation (2 available)
Myd88tm1Aki mutation (9 available); any Myd88 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased IgM level ( J:115059 )
• serum levels are increased compared to wild-type

hematopoietic system
increased IgM level ( J:115059 )
• serum levels are increased compared to wild-type




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory